Project/scholarship details
- Project/scholarship ID
105085
- Reference
PTDC/EBB-EBI/105085/2008
- FundRef URI
- Funder
FCT - Fundação para a Ciência e a Tecnologia, I.P.
- Funder's country
Portugal
- Funding program
5876-PPCDTI
- Funding amount
171,112.00 €
- Start date
2010-06-01
- End date
2013-11-30
Documents
A review of current and emergent biofilm control strategies
Simões, M.; Simões, Lúcia C.; Vieira, M. J.Microbial adhesion to surfaces and the consequent biofilm formation has been documented in many different environments. Biofilms constitute a protected mode of growth that allows microorganisms to survival in hostile environments, being their physiology and behavior significantly different from their planktonic counterparts. In dairy industry, biofilms may be a source of recalcitrant contaminations, causing foo...
Green anti-biofouling strategies
Simões, Manuel Lopes; Simões, Lúcia C.Microbial adhesion to surfaces and consequent biofouling formation has been documented in many different environments. Biofilms constitute a protected mode of growth that allows microorganisms to survival in hostile environments, being their physiology and behavior significantly different from their planktonic counterparts. Their eradication is difficult not only due to their phenotype but also associated with ...
The effects of glutaraldehyde on the control of single and dual biofilms of Bac...
Simões, Lúcia C.; Lemos, Madalena; Araújo, Paula; Pereira, Ana M.; Simões, M.Glutaraldehyde (GLUT) was evaluated for control of single and dual species biofilms of Bacillus cereus and Pseudomonas fluorescens on stainless steel surfaces using a chemostat system. The biofilms were characterized in terms of mass, cell density, total and matrix proteins and polysaccharides. The control action of GLUT was assessed in terms of inactivation and removal of biofilm. Post-biocide action was chara...
Antibacterial activity of phenyl isothiocyanate on Escherichia coli and Staphyl...
Abreu, Ana C.; Borges, Anabela; Simões, Lúcia C.; Saavedra, Maria J.; Simões, M.The present study has been aimed to assess the antibacterial effects of the glucosinolate hydrolysis product phenyl isothiocyanate (PITC) against Escherichia coli and Staphylococcus aureus. Aspects on the antibacterial mode of action of PITC have also been characterized, such as the changes on surface physicochemical characteristics and membrane damage. The minimum inhibitory concentration of PITC was 1000 µg/m...
Biofilms in drinking water: problems and solutions
Simões, Lúcia C.; Simões, M.The main goal of water companies is to deliver to each consumer microbiologically safe drinking water (DW), adequate in quantity and delivery pressure and acceptable in terms of taste, odour and appearance. Drinking water distribution systems (DWDS) are known to harbour biofilms, even in the continuous presence of a disinfectant. These biofilms are a source of planktonic bacteria, which will remain present when...
The action of selected isothiocyanates on bacterial biofilm prevention and control
Borges, A.; Simões, Lúcia C.; Saavedra, Maria J.; Simões, M.The activity of two selected isothiocyanates (ITCs), allylisothiocyanate (AITC) and 2-phenylethy-lisothiocyanate (PEITC) was evaluated on the prevention and control of biofilms formed by Escherichia coli, Pseudomonas aeruginosa, Staphylococcus aureus and Listeria monocytogenes. In addition, the effect of ITCs was also tested on planktonic cell susceptibility, bacterial motility and adhesion. Biofilm prevention ...
Combinatorial activity of flavonoids with antibiotics against drug resistant St...
Abreu, Ana Cristina; Serra, Sofia Cravino; Borges, Anabela; Saavedra, Maria J.; Mcbain, Andrew J.; Salgado, A. J.; Simões, ManuelThe use of resistance-modifying agents is a potential strategy that is used to prolong the effective life of antibiotics in the face of increasing antibiotic resistance. Since certain flavonoids are potent bacterial efflux pump inhibitors, we assessed morin, rutin, quercetin, hesperidin, and (+)-catechin for their combined activity with the antibiotics ciprofloxacin, tetracycline, erythromycin, oxacillin, and a...
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