Project/scholarship details
- Project/scholarship ID
115316
- Reference
PTDC/PSI-PCL/115316/2009
- FundRef URI
- Funder
FCT - Fundação para a Ciência e a Tecnologia, I.P.
- Funder's country
Portugal
- Funding program
5876-PPCDTI
- Funding amount
166,518.00 €
- Start date
2011-03-01
- End date
2014-08-31
Documents
Cognitive functioning in children and adults with Smith-Magenis syndrome
Osório, Ana Alexandra Caldas; Cruz, Raquel; Sampaio, Adriana; Garayzábal Heinze, Elena; Carracedo, Ángel; Férnandez-Prieto, MontserratSmith-Magenis Syndrome (SMS) is a genetic neurodevelopmental disorder caused by a microdeletion on chromosome 17p11.2. This syndrome is characterized by a distinctive profile of physical, medical and neuropsychological characteristics. The latter include general mental disability, with the majority of individuals falling within the mild to moderate range. This study reports a detailed cognitive assessment of ch...
A psicologia como neurociência cognitiva: implicações para a compreensão dos pr...
Gonçalves, Óscar F.; Sampaio, Adriana; Mesquita, Ana Raquel Marcelino; Petrosyan, Agavni; Pinheiro, Ana P.; Carvalho, Sandra Conceição RibeiroO presente artigo procura ilustrar o modo como os desenvolvimentos das neurociências cognitivas poderão ajudar a compreender alguns dos processos psicológicos básicos e, simultaneamente, ser traduzidos para importantes domínios da psicologia aplicada, particularmente no domínio clínico. Exemplificaremos a partir de algumas linhas de investigação programática em curso nas diferentes subsecções do Laboratório de ...
Autism spectrum symptoms in Smith-Magenis syndrome and Williams syndrome: compa...
Osório, Ana Alexandra Caldas; Sampaio, Adriana; Martínez Regueiro, Rocío; Garayzábal Heinze, Elena; Carracedo, Ángel; Fernández Prieto, MontseObjectives: Genetic syndromes with distinctive cognitive and behavioural phenotypes - such as Smith-Magenis syndrome (SMS) and Williams syndrome (WS) - offer unique opportunities to explore the links between specific genes and neurodevelopmental disorders. While some studies have reported the occurrence of autistic symptoms in SMS, evidence for such symptomatology in WS is scarcer. This study is the first to co...
Default mode network dissociation in depressive and anxiety states
Coutinho, Joana Fernandes Pereira; Fernandes, Sara Catarina da Veiga; Soares, José Miguel Montenegro; Maia, Liliana Filipa Costa; Gonçalves, Óscar F.The resting state brain networks, particularly the Default Mode Network (DMN), have been found to be altered in several psychopathological conditions such as depression and anxiety. In this study we hypothesized that cortical areas of the DMN, particularly the anterior regions - medial prefrontal cortex and anterior cingulate cortex - would show an increased functional connectivity associated with both anxiety ...
Altered functional connectivity of the default mode network in Williams syndrom...
Sampaio, Adriana; Moreira, Pedro Miguel Silva; Osório, Ana Alexandra Caldas; Magalhães, Ricardo José Silva; Vasconcelos, Cristiana; Fernandez, MontseResting state brain networks are implicated in a variety of relevant brain functions. Importantly, abnormal patterns of functional connectivity (FC) have been reported in several neurodevelopmental disorders. In particular, the Default Mode Network (DMN) has been found to be associated with social cognition. We hypothesize that the DMN may be altered in Williams syndrome (WS), a neurodevelopmental genetic disor...
Psychopathology and behavior problems in children and adolescents with Williams...
Osório, Ana Alexandra Caldas; Rossi, Natalia F.; Gonçalves, Óscar F.; Sampaio, Adriana; Giacheti, Célia M.Several studies have documented the high prevalence of psychopathology and behavior problems in Williams syndrome (WS). However, the links between cognitive development and such symptoms need further clarification. Our study aims to expand current knowledge on levels of behavior problems and its links to cognition in a sample of Brazilian individuals with WS. A total of 25 children and adolescents with WS and t...
Insights on Social Behavior From Studying Williams Syndrome
Sampaio, Adriana; Belsky, Jay; Soares, Isabel; Mesquita, A. R.; Osório, Ana; Gonçalves, Óscar F.Central to the developmental psychopathology perspective is the claim that studying normal and atypical development are related. In this article, we argue that studying a naturally occurring genetic condition—Williams syndrome—provides insight into social behavior in typically developing children. Toward this end, we describe the social phenotype of Williams syndrome, then offer three insights regarding biologi...
Empathy by default: correlates in the brain at rest
Silva, Patrícia Oliveira; Maia, Liliana Filipa Costa; Coutinho, Joana Fernandes Pereira; Frank, Brandon; Soares, José Miguel MontenegroBackground: Empathy, defined as the ability to access and respond to the inner world of another person, is a multidimensional construct involving cognitive, emotional and self-regulatory mechanisms. Neuroimaging studies report that empathy recruits brain regions which are part of the social cognition network. Among the different resting state networks, the Default Mode Network (DMN) may be of particular interes...
Report
Embed
<script type="text/javascript">
<!--
document.write('<div id="rcaap-widget"></div>');
document.write('<script type="text/javascript" src="https://www.rcaap.pt/snippet?resource=documents&project=FCT%2F5876-PPCDTI%2F115316&fields=id,titles,creators,issueDate,link,descriptions"></script>');
-->
</script>