Project/scholarship details

  • Funder

    FCT - Fundação para a Ciência e a Tecnologia, I.P.

  • Funder's country

    Portugal

  • Funding program

    5876-PPCDTI

  • Funding amount

    168,000.00 €

  • Start date

    2011-02-01

  • End date

    2014-07-31

Documents

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Design of cationic lipid nanoparticles for ocular delivery: Development, charac...

Fangueiro, JF; Andreani, T; Egea, MA; Garcia, ML; Souto, SB; Silva, AM; Souto, EB

In the present study we have developed lipid nanoparticle (LN) dispersions based on a multiple emulsion technique for encapsulation of hydrophilic drugs or/and proteins by a full factorial design. In order to increase ocular retention time and mucoadhesion by electrostatic attraction, a cationic lipid, namely cetyltrimethylammonium bromide (CTAB), was added in the lipid matrix of the optimal LN dispersion obtai...

Date: 2014   |   Origin: Repositório Científico do Hospital de Braga
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